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CytoSoft Discovery Kit, 6-Well Plates
The rigidity of the substrate to which cells adhere can have a profound effect on cell morphology and gene expression. CytoSoft products provide a tool to culture cells on substrates with various rigidities covering a broad physiological range. On the bottom of each well, there is a thin layer of specially formulated biocompatible silicone, whose elastic modulus (rigidity) is carefully measured and certified. The surfaces of the gels in CytoSoft products are functionalized to form covalent bonds with amines on proteins. This chemical functionalization is stable and the reaction does not require a catalyst, facilitating the coating of the gel surfaces with matrix proteins and plating cells.
This CytoSoft product, Catalog Number 5190-7EA, has various elastic moduli of approximately 0.2, 0.5, 2, 8, 16, 32 and 64 kPa in 7 individual 6-well plates. The thickness of the silicone gel is uniform with a ~0.5 mm thick layer of silicone in each dish that is fully compatible with mammalian cell cultures. The plates are packaged individually, sterilized using irradiation and provided with 7 dishes per package.
Rigidity (elastic modules) 0,2 / 0,5 / 2 / 8 / 16 / 32 / 64 kPa
7 Dishes (6 well)