Organotypic 3-D Cell Culture Models

Reconstructed Human Epidermis

CellSystems offers Reconstructed human Epidermis (RhE) for more than a decade.

The initial  name was "Epidermal Skin Test - EST-1000" later "EST1000" and became "epiCS®" in 2012.
(This name chance did not imply any technical changes to the product nor to any regulatory acceptance.)

In 2013 we launched the pigmented RhE - "epiCS®-M". It is available with melanocytes from donors of three different phototypes: Caucausian, Afro-American and Asian-Caucasian.
Growing interest for RhE and growing demands for specific technical / scientific support drove us to create a web-based resource centre for RhE:

Very recently, In 2017 we launched the human reconstructed full thickness skin epiCS®-FT. It contains a dermis and an epidermis equivalent. More information will follow in due course. provides up to date protocols, OECD Test Guidelines, SOP and many more helpful documents on RhE.

On the CellSystems web-site in sections on epiCS®, epiCS®-M and epiCS®-FTyou find information on:
Products (epiCS, epiCS-M, epiCS-FT and related products)
Validation services
Contract services & more