CellSystems

Human Skin Models

Human reconstructed skin have become increasingly important during the last few years in different fields. Reconstructed epidermis already replace animal testing for skin corrosion and skin irritation testing. They are used for substance testing in the regulatory context of the cosmetics directive and under the REACH legislation. More complex skin models are established research tools for the cosmetics and pharmaceutical industry as well as for academia. Especially in this area, the diversity of skin models and applications is rapidly growing. CellSystems offers the epidermis model Epidermal Skin Test 1000, EST1000, and customized services.

EST1000 (Epidermal Skin Test 1000)

A three dimensional human epidermis model. It consists of normal primary human epidermal keratinocytes. The cellular structure of EST1000 resembles that of the fully differentiated natural epidermis showing a base membrane, proliferating keratinocytes and a stratum corneum with an intact barrier function.

EST1000 is the ECVAM accepted epidermal model for regulatory toxicity testing.

Services

CellSystems manufactures customized reconstructed skin models and offers contract research and testing services. Please, contact us for more information.

CellSystems laboratory facility is DIN ISO 9001:2008 certified for skin model production and testing services.