α2 –Plasmin Inhibitor

Cat.-Nr.: HA2AP-0230

Specifications PDF

Structure

Circulates as single chain molecule consisting of 452 amino acids

Formulation

50 mM Potassium phosphate, 7.5 mM KCl, 0.075 mM EDTA, pH 7.4

Storage

-80 Celsius

Size

100 µg

Shipping

dry ice

Purity

>95%

Localization

Plasma

Concentration in plasma

69 µg/ml

Mode of action

Inhibits plasmin by forming an irreversible complex with the catalytic active site. Prevents the binding of plasmin to fibrin. Cross-linked by factor XIIIa to fibrin.

Molecular weight

58,700 single-chain (determined from amino acid sequence and 14% carbohydrate) and 67,000 (determined by SDS-PAGE)

Extinction coeff

7.03

Percent carbohydrate

0%